Glycoscience Group

Organisational unit: Research Group

Organisation Profile

The Glycoscience group headed by Professor Jukka Finne is engaged with the biology of carbohydrates, the most abundant biological molecules of nature, involved in the biology of all living organisms. Glycans have received little attention due to lack of efficient tools to probe their complex structures and properties.

The group has focused on the study of two main topics of carbohydrate interactions: the role of polysialic acid, a developmentally regulated carbohydrate moiety of cell adhesion molecules originally discovered by us, in the childhood cancer neuroblastoma, as well as the role of cell surface carbohydrates in the adhesion of pathogenic bacteria to the cells of our body.

Latest research outputs

  1. Mu transpososome activity-profiling yields hyperactive MuA variants for highly efficient genetic and genome engineering

    Research output: Contribution to journalArticleScientificpeer-review

  2. Rationally designed chemically modified glycodendrimer inhibits Streptococcus suis adhesin SadP at picomolar concentrations

    Research output: Contribution to journalArticleScientificpeer-review

  3. Internalization of a polysialic acid-binding Escherichia coli bacteriophage into eukaryotic neuroblastoma cells

    Research output: Contribution to journalArticleScientificpeer-review

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