PREP in neurodegenerative disorders

Organisational unit: Research Group

Organisation Profile

We are studying the role of prolyl oligopeptidase (PREP, formerly known as POP) on disease progression and neuronal toxicity in neurodegenerative disorders with protein aggregation. These disorders involve several serious diseases such as Alzheimer’s and Parkinson’s diseases, and several more rare neurodegenerative conditions. Based on PREP inhibitors, we are developing novel and disease-modifying drug therapies to stop the neuronal death in Alzheimer's and Parkinson's diseases.

Read more on our website

Latest research outputs

  1. New tricks of prolyl oligopeptidase inhibitors - A common drug therapy for several neurodegenerative diseases

    Research output: Contribution to journalReview ArticleScientificpeer-review

  2. Protein kinase C-activating isophthalate derivatives mitigate Alzheimer's disease-related cellular alterations

    Research output: Contribution to journalArticleScientificpeer-review

ID: 120362139