Department of Diagnostics and Therapeutics

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  1. Muuntohuumeita käyttäneet yliannostuspotilaat Helsingin ensihoidossa vuosina 2009 - 2012

    Järvinen, T. & Boyd, J., 2015, In : Duodecim. 131, 18, p. 1659-1666 8 p.

    Research output: Contribution to journalArticleScientificpeer-review

  2. The level of evidence for emergency department performance indicators: systematic review

    Madsen, M., Kiuru, S., Castren, M. & Kurland, L., 1 Oct 2015, In : European Journal of Emergency Medicine. 22, 5, p. 298-305 8 p.

    Research output: Contribution to journalReview ArticleScientificpeer-review

  3. Nonelective surgery at night and in-hospital mortality Prospective observational data from the European Surgical Outcomes Study

    van Zaane, B., van Klei, W. A., Buhre, W. F., Bauer, P., Boerma, E. C., Hoeft, A., Metnitz, P., Moreno, R. P., Pearse, R., Pelosi, P., Sander, M., Vallet, B., Pettila, V., Vincent, J-L., Rhodes, A., European Soc Intensive Care Med & European Soc Anaesthesiology, Jul 2015, In : European Journal of Anaesthesiology. 32, 7, p. 477-485 9 p.

    Research output: Contribution to journalArticleScientificpeer-review

  4. Mechanism-based population pharmacokinetic and pharmacodynamic modeling of intravenous and intranasal dexmedetomidine in healthy subjects

    Yoo, H., Iirola, T., Vilo, S., Manner, T., Aantaa, R., Lahtinen, M., Scheinin, M., Olkkola, K. T. & Jusko, W. J., Oct 2015, In : European Journal of Clinical Pharmacology. 71, 10, p. 1197-1207 11 p.

    Research output: Contribution to journalArticleScientificpeer-review

  5. Post resuscitation care of out-of-hospital cardiac arrest patients in the Nordic countries: a questionnaire study

    Saarinen, S., Castren, M., Virkkunen, I. & Kamarainen, A., 22 Aug 2015, In : Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine. 23, 6 p., 60.

    Research output: Contribution to journalArticleScientificpeer-review

  6. Kosteus- ja homealtistusoireyhtymä on tunnistettava ja tunnustettava

    Tuuminen, T., 2015, In : Erikoislääkäri. 25, 3, p. 88-89 2 p.

    Research output: Contribution to journalArticleProfessional

  7. From laboratory to clinical practice: Dabigatran effects on thrombin generation and coagulation in patient samples

    Helin, T. A., Lemponen, M., Hjemdahl, P., Ronquist-Nii, Y., Lassila, R. & Joutsi-Korhonen, L., 1 Jul 2015, In : Thrombosis Research. 136, 1, p. 154-160 7 p.

    Research output: Contribution to journalArticleScientificpeer-review

  8. Do we need MRI quality assurance: experience from a multi-unit imaging center with 14 MRI systems

    Kuusela, L., Timonen, M. H., Teemu, M., Juha, P., Ihalainen, T. M., Uusi-Simola, J., Kaasalainen, T. T., Savolainen, S. E. & Sipilä, O., 2015, In : Insights into Imaging. 2015, 6 (Suppl), p. 73 1 p., B-0321.

    Research output: Contribution to journalConference articleScientificpeer-review

  9. Patients with complex regional pain syndrome overestimate applied force in observed hand actions

    Hotta, J., Harno, H., Nummenmaa, L., Kalso, E., Hari, R. & Forss, N., Oct 2015, In : European Journal of Pain. 19, 9, p. 1372-1381 10 p.

    Research output: Contribution to journalArticleScientificpeer-review

  10. Enhanced recovery protocol after liver resection

    Savikko, J., Ilmakunnas, M., Makisalo, H., Nordin, A. & Isoniemi, H., Nov 2015, In : British Journal of Surgery. 102, 12, p. 1526-1532 7 p.

    Research output: Contribution to journalArticleScientificpeer-review

  11. Arthroscopic resection of medial plica of the knee in young adults

    Weckstrom, M., Niva, M. H., Lamminen, A., Mattila, V. M. & Pihlajamaki, H. K., Mar 2010, In : Knee. 17, 2, p. 103-107 5 p.

    Research output: Contribution to journalArticleScientificpeer-review

  12. Patient Satisfaction and Short-Term Outcome in Elective Cranial Neurosurgery

    Reponen, E., Tuominen, H., Hernesniemi, J. & Korja, M., Nov 2015, In : Neurosurgery (Baltimore). 77, 5, p. 769-775 7 p.

    Research output: Contribution to journalArticleScientificpeer-review

  13. Sleep deprivation increases brain serotonin turnover in the rat

    Asikainen, M., Toppila, J., Alanko, L., Ward, DJ., Stenberg, D. & Porkka-Heiskanen, T., 6 May 1997, In : NeuroReport. 8, 7, p. 1577-1582 6 p.

    Research output: Contribution to journalArticleScientificpeer-review

  14. The effect of REM sleep deprivation on somatostatin and growth hormone-releasing hormone gene expression in the rat hypothalamus

    Toppila, J., Asikainen, M., Alanko, L., Turek, FW., Stenberg, D. & Porkka-Heiskanen, T., Jun 1996, In : Journal of Sleep Research. 5, 2, p. 115-122 8 p.

    Research output: Contribution to journalArticleScientificpeer-review

  15. Leikkauksenjälkeisen kivun hoito

    Kontinen, V. & Hamunen, K., 2015, In : Duodecim. 131, 20, p. 1921-1928 8 p.

    Research output: Contribution to journalArticleScientificpeer-review

  16. Amputaatiopotilaan akuutti kipu - FinAPain-1

    Plato, H. V. & Kontinen, V., 2015, In : Kipuviesti : Suomen kivuntutkimusyhdistyksen jäsenlehti.. 18, 2, p. 15-22 8 p.

    Research output: Contribution to journalArticleProfessional

  17. Terveydenhuollon laitteet ja tarvikkeet

    Randell, T., 2015, In : Finnanest.. 48, 4, p. 344-347 4 p.

    Research output: Contribution to journalArticleProfessional

  18. Pharmacokinetics of amrinone in neonates and infants

    Laitinen, P., Ahonen, J., Olkkola, KT., Peltola, K., Rautiainen, P. & Räsänen, J., Aug 2000, In : Journal of Cardiothoracic and Vascular Anesthesia. 14, 4, p. 378-382 5 p.

    Research output: Contribution to journalArticleScientificpeer-review

  19. Effect of erythromycin and itraconazole on the pharmacokinetics of intravenous lignocaine

    Isohanni, MH., Neuvonen, PJ., Palkama, VJ. & Olkkola, KT., Sep 1998, In : European Journal of Clinical Pharmacology. 54, 7, p. 561-565 5 p.

    Research output: Contribution to journalArticleScientificpeer-review

  20. Fluconazole but not itraconazole decreases the metabolism of losartan to E-3174

    Kaukonen, KM., Olkkola, KT. & Neuvonen, PJ., Feb 1998, In : European Journal of Clinical Pharmacology. 53, 6, p. 445-449 5 p.

    Research output: Contribution to journalArticleScientificpeer-review

  21. Validation of air tonometric measurement of gastric regional concentrations of CO2 in critically ill septic patients

    Heinonen, PO., Jousela, IT., Blomqvist, KA., Olkkola, KT. & Takkunen, OS., May 1997, In : Intensive Care Medicine. 23, 5, p. 524-529 6 p.

    Research output: Contribution to journalArticleScientificpeer-review

  22. PLASMA-CONCENTRATIONS OF TRIAZOLAM ARE INCREASED BY CONCOMITANT INGESTION OF GRAPEFRUIT JUICE

    HUKKINEN, SK., VARHE, A., Olkkola, K. & NEUVONEN, PJ., Aug 1995, In : Clinical Pharmacology and Therapeutics. 58, 2, p. 127-131 5 p.

    Research output: Contribution to journalArticleScientificpeer-review

  23. Time course of potentiation of mivacurium by halothane and isoflurane in children

    Meretoja, OA., Wirtavuori, K., Taivainen, T. & Olkkola, KT., Feb 1996, In : British Journal of Anaesthesia. 76, 2, p. 235-238 4 p.

    Research output: Contribution to journalArticleScientificpeer-review

  24. A POTENTIALLY HAZARDOUS INTERACTION BETWEEN ERYTHROMYCIN AND MIDAZOLAM

    Olkkola, K., ARANKO, K., LUURILA, H., HILLER, A., SAARNIVAARA, L., HIMBERG, JJ. & NEUVONEN, PJ., Mar 1993, In : Clinical Pharmacology and Therapeutics. 53, 3, p. 298-305 8 p.

    Research output: Contribution to journalArticleScientificpeer-review

  25. COMPARISON OF THE VENTILATORY EFFECTS OF MORPHINE AND BUPRENORPHINE IN CHILDREN

    HAMUNEN, K., Olkkola, K. & MAUNUKSELA, EL., Jul 1993, In : Acta Anaesthesiologica Scandinavica. 37, 5, p. 449-453 5 p.

    Research output: Contribution to journalArticleScientificpeer-review

  26. Pregnancy Complications Following Prenatal Exposure to SSRIs or Maternal Psychiatric Disorders: Results From Population-Based National Register Data

    Malm, H., Sourander, A., Gissler, M., Gyllenberg, D., Hinkka-Yli-Salomaki, S., McKeague, I. W., Artama, M. & Brown, A. S., Dec 2015, In : American Journal of Psychiatry. 172, 12, p. 1224-1232 9 p.

    Research output: Contribution to journalArticleScientificpeer-review

  27. Neutrophil Extracellular Traps Provide a Grip on the Enigmatic Pathogenesis of Acute Pancreatitis

    Korhonen, J. T., Dudeja, V., Dawra, R., Kubes, P. & Saluja, A., Dec 2015, In : Gastroenterology. 149, 7, p. 1682-1685 4 p.

    Research output: Contribution to journalArticleScientific

  28. Preoperative identification of neurosurgery patients with a high risk of in-hospital complications: a prospective cohort of 418 consecutive elective craniotomy patients

    Reponen, E., Korja, M., Niemi, T., Silvasti-Lundell, M., Hernesniemi, J. & Tuominen, H., Sep 2015, In : Journal of Neurosurgery. 123, 3, p. 594-604 11 p.

    Research output: Contribution to journalArticleScientificpeer-review

  29. A comparison of serum and tissue hCG beta as prognostic markers in colorectal cancer

    Lundin, M., Nordling, S., Carpelan-Holmstrom, M., Louhimo, J., Alfthan, H., Stenman, U. H. & Haglund, C., 2000, In : Anticancer Research. 20, 6D, p. 4949-4951 3 p.

    Research output: Contribution to journalArticleScientificpeer-review

  30. In Reply: Patient Satisfaction and Short-term Outcome in Elective Cranial Neurosurgery

    Reponen, E., Tuominen, H. & Korja, M., Jan 2016, In : Neurosurgery (Baltimore). 78, 1, p. E163-E164 2 p.

    Research output: Contribution to journalArticleScientific

  31. External validation of the Norwegian survival prediction model in trauma after major trauma in Southern Finland.

    Raj, R., Brinck, T., Skrifvars, M. & Handolin, L., 2016, In : Acta Anaesthesiologica Scandinavica. 60, 1, p. 48-58 11 p.

    Research output: Contribution to journalArticleScientificpeer-review

  32. Milloin liikunta on pakkomielle?

    Uusitalo, A., 2010, In : Suomen lääkärilehti. 65, 47, p. 3870-3871 2 p.

    Research output: Contribution to journalArticleScientific

  33. Aivojen yksifotoniemissiotomografia (SPET)

    Loimaala, A. & Uusitalo, A., 2015, Neurologia (e). Soinila, S. & Kaste, M. (eds.). Helsinki: Duodecim Oppiportti , neu00033 (006.020)

    Research output: Chapter in Book/Report/Conference proceedingChapterProfessional

  34. Goal-Directed Resuscitation for Patients with Early Septic Shock

    Peake, S. L., Delaney, A., Bailey, M., Bellomo, R., Cameron, P. A., Cooper, D. J., Higgins, A. M., Holdgate, A., Howe, B. D., Webb, S. A. R., Williams, P., ARISE Investigators, ANZICS Clinical Trials Grp & Pettilä, V., 16 Oct 2014, In : New England Journal of Medicine. 371, 16, p. 1496-1506 11 p.

    Research output: Contribution to journalArticleScientificpeer-review

  35. Nosiseptiivinen kipu syöpätaudeissa

    Kalso, E., 2013, Syöpätaudit. Joensuu, H., Roberts, P. J., Kellokumpu-Lehtinen, P-L., Jyrkkiö, S., Kouri, M. & Teppo, L. (eds.). 5. uud. p. ed. Helsinki: Duodecim, p. 878-879 2 p.

    Research output: Chapter in Book/Report/Conference proceedingChapterProfessional

  36. Syövän hoidon aiheuttama kipu

    Kalso, E., 2013, Syöpätaudit. Joensuu, H., Roberts, P. J., Kellokumpu-Lehtinen, P-L., Jyrkkiö, S., Kouri, M. & Teppo, L. (eds.). 5. uud. p. ed. Helsinki: Duodecim, p. 880-881 2 p.

    Research output: Chapter in Book/Report/Conference proceedingChapterProfessional

  37. Syöpään liittyvän kivun hoitoperiaatteet

    Kalso, E., 2013, Syöpätaudit. Joensuu, H., Roberts, P. J., Kellokumpu-Lehtinen, P-L., Jyrkkiö, S., Kouri, M. & Teppo, L. (eds.). 5. uud. p. ed. Helsinki: Duodecim, p. 884 1 p.

    Research output: Chapter in Book/Report/Conference proceedingChapterProfessional

  38. Analysis of infant cortical synchrony is constrained by the number of recording electrodes and the recording montage

    Tokariev, A., Vanhatalo, S. & Palva, J. M., Jan 2016, In : Clinical Neurophysiology. 127, 1, p. 310-323 14 p.

    Research output: Contribution to journalArticleScientificpeer-review

  39. Reference Values for Echocardiography in Middle-Aged Population: The Cardiovascular Risk in Young Finns Study

    Ruohonen, S., Koskenvuo, J. W., Wendelin-Saarenhovi, M., Savontaus, M., Kahonen, M., Laitinen, T., Lehtimaki, T., Jokinen, E., Viikari, J., Juonala, M., Taittonen, L., Tossavainen, P., Kallio, M., Bax, J. J. & Raitakari, O., Feb 2016, In : Echocardiography. 33, 2, p. 193-206 14 p.

    Research output: Contribution to journalArticleScientificpeer-review

  40. PLASMA HEME OXYGENASE-1 IN PATIENTS RESUSCITATED FROM OUT-OF-HOSPITAL CARDIAC ARREST

    Siren, J., Vaahersalo, J., Skrifvars, M., Pettilä, V., Tiainen, M., Tikkanen, I., Lakkisto, P. & FINNRESUSCI Study Grp, Mar 2016, In : Shock (Philadelphia). 45, 3, p. 320-325 6 p.

    Research output: Contribution to journalArticleScientificpeer-review

  41. Urinary Biomarkers Indicative of Apoptosis and Acute Kidney Injury in the Critically Ill

    Vaara, S. T., Lakkisto, P., Immonen, K., Tikkanen, I., Ala-Kokko, T., Pettila, V. & FINNAKI Study Grp, 26 Feb 2016, In : PLoS One. 11, 2, 13 p., 0149956.

    Research output: Contribution to journalArticleScientificpeer-review

  42. Epidemiology of RBC Transfusions in Patients With Severe Acute Kidney Injury: Analysis From the Randomized Evaluation of Normal Versus Augmented Level Study

    Bellomo, R., Martensson, J., Kaukonen, K-M., Lo, S., Gallagher, M., Cass, A., Myburgh, J., Finfer, S., Randomized Evaluation Normal Versu & Australian New Zealand Intensive C, May 2016, In : Critical Care Medicine. 44, 5, p. 892-900 9 p.

    Research output: Contribution to journalArticleScientificpeer-review

  43. Cardiac repolarization in recently postmenopausal women with or without hot flushes

    Lantto, H., Mikkola, T. S., Tuomikoski, P., Viitasalo, M., Vaananen, H., Sovijarvi, A. R. A. & Haapalahti, P., May 2016, In : Menopause. 23, 5, p. 528-534 7 p.

    Research output: Contribution to journalArticleScientificpeer-review

  44. Comparison of train-of-four ratios measured with Datex-Ohmeda's M-NMT MechanoSensor (TM) and M-NMT ElectroSensor (TM)

    Salminen, J., van Gils, M., Paloheimo, M. & Yli-Hankala, A., Jun 2016, In : Journal of Clinical Monitoring and Computing. 30, 3, p. 295-300 6 p.

    Research output: Contribution to journalArticleScientificpeer-review

  45. Obesity Is Associated With Low NAD(+)/SIRT Pathway Expression in Adipose Tissue of BMI-Discordant Monozygotic Twins

    Jukarainen, S., Heinonen, S., Ramo, J. T., Rinnankoski-Tuikka, R., Rappou, E., Tummers, M., Muniandy, M., Hakkarainen, A., Lundbom, J., Lundbom, N., Kaprio, J., Rissanen, A., Pirinen, E. & Pietilainen, K. H., Jan 2016, In : Journal of Clinical Endocrinology and Metabolism. 101, 1, p. 275-283 9 p.

    Research output: Contribution to journalArticleScientificpeer-review

  46. Randomized evaluation of fibrinogen vs placebo in complex cardiovascular surgery (REPLACE): a double-blind phase III study of haemostatic therapy

    Rahe-Meyer, N., Levy, J. H., Mazer, C. D., Schramko, A., Klein, A. A., Brat, R., Okita, Y., Ueda, Y., Schmidt, D. S., Ranganath, R. & Gill, R., Jul 2016, In : British Journal of Anaesthesia. 117, 1, p. 41-51 11 p.

    Research output: Contribution to journalArticleScientificpeer-review

  47. Relevance of truncating titin mutations in dilated cardiomyopathy

    Akinrinade, O., Alastalo, T-P. & Koskenvuo, J., Jul 2016, In : Clinical Genetics. 90, 1, p. 49-54 6 p.

    Research output: Contribution to journalArticleScientificpeer-review

  48. Weight Loss Is Associated With Increased NAD(+)/SIRT1 Expression But Reduced PARP Activity in White Adipose Tissue

    Rappou, E., Jukarainen, S., Rinnankoski-Tuikka, R., Kaye, S. M., Heinonen, S., Hakkarainen, A., Lundbom, J., Lundbom, N., Saunavaara, V., Rissanen, A., Virtanen, K. A., Pirinen, E. & Pietilainen, K. H., Mar 2016, In : Journal of Clinical Endocrinology and Metabolism. 101, 3, p. 1263-1273 11 p.

    Research output: Contribution to journalArticleScientificpeer-review

  49. A comparison of simple reaction time, visual discrimination and critical flicker fusion frequency in professional divers at elevated pressure

    Tikkinen, J., Wuorimaa, T. & Siimes, M. A., Jun 2016, In : Diving and Hyperbaric Medicine. 46, 2, p. 82-86 5 p.

    Research output: Contribution to journalArticleScientificpeer-review