Mark Daly


Curriculum Vitae

Mark Daly, Ph.D. is the Director of the Institute of Molecular Medicine Finland FIMM, where he succeeds Academy Professor Jaakko Kaprio as of February 1, 2018.  Mark was recruited from Harvard Medical School – where he was the founding chief of the Analytic and Translational Unit at the Massachusetts General Hospital from 2011 - and the Broad Institute of MIT and Harvard.

While primarily based in Finland, he retains an active role in Boston at HMS/MGH and as an Institute Member at the Broad Institute, where he is establishing a close partnership between FIMM and the Broad Institute.

Mark’s primary research focus is discovery of genes involved in human disease as a means of providing both insights for therapeutic development as well as improved diagnostics for individual patients.  His lab has developed many foundational computational tools and statistical techniques in genome mapping, linkage and association, and automated interpretation of laboratory data.  The lab has a significant and longstanding commitment in two major medical areas: the inflammatory bowel diseases (Crohn’s and ulcerative colitis) and neuropsychiatric disease (autism and schizophrenia) and Mark has led international consortium efforts large-scale gene mapping efforts in each of these areas – co-chairing the International IBD Genetics Consortium (, the Psychiatric Genomics Consortium ( and the Autism Sequencing Consortium. With Dr. Palotie, he has helped design and launch the FinnGen Project ( as a transformative public-private partnership.  Mark Daly has been an author on more than 450 peer-reviewed manuscripts with a total of more than 200,000 citations, has an h-index of 178, and has been listed by Thompson ISI/Science Watch in 2008 and 2010 as one of the top ten authors ranked by number of high-impact papers.  Mark was the recipient of the Curt Stern Award from the American Society of Human Genetics in 2014 and was elected to the National Academy of Medicine in 2017.


Latest publications

  1. Case-control analysis identifies shared properties of rare germline variation in cancer predisposing genes

    Artomov, M., Joseph, V., Tiao, G., Thomas, T., Schrader, K., Klein, R. J., Kiezun, A., Gupta, N., Margolin, L., Stratigos, A. J., Kim, I., Shannon, K., Ellisen, L. W., Haber, D., Getz, G., Tsao, H., Lipkin, S. M., Altshuler, D., Offit, K. & Daly, M. J., May 2019, In : European Journal of Human Genetics. 27, 5, p. 824-828 5 p.

    Research output: Contribution to journalArticleScientificpeer-review

  2. Mutations in ATP13A2 (PARK9) are associated with an amyotrophic lateral sclerosis-like phenotype, implicating this locus in further phenotypic expansion

    Spataro, R., Kousi, M., Farhan, S. M. K., Willer, J. R., Ross, J. P., Dion, P. A., Rouleau, G. A., Daly, M. J., Neale, B. M., La Bella, V. & Katsanis, N., 16 Apr 2019, In : Human Genomics. 13, 10 p., 19.

    Research output: Contribution to journalArticleScientificpeer-review

  3. Clinical use of current polygenic risk scores may exacerbate health disparities

    Martin, A. R., Kanai, M., Kamatani, Y., Okada, Y., Neale, B. M. & Daly, M. J., Apr 2019, In : Nature Genetics. 51, 4, p. 584-591 8 p.

    Research output: Contribution to journalArticleScientificpeer-review

View all (44) »

Latest activities

  1. Juha Karjalainen

    Mark Daly (Host)
    18 Dec 201819 Jan 2019

    Activity: Hosting a visitor typesAcademic visit at UH

  2. Talk: Finnish medical and population data: powering predictive medicine and disease prevention

    Mark Daly (Speaker)
    22 Nov 2018

    Activity: Talk or presentation typesInvited talk

  3. Talk: Finnish opportunities to translate genomic knowledge into population health

    Mark Daly (Invited speaker)
    14 Nov 2018

    Activity: Talk or presentation typesInvited talk

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