Jorma Keski-Oja


Description of research and teaching

Supervision of academic dissertations (12 finished by 2010) and follow-up of students:

Marikki Laiho, M.D. Ph.D.: Transforming growth factor-ß in the regulation of  extracellular proteolysis of cultured cells, University of Helsinki, 1988. 

Katri Koli, Ph.D.: Growth-inhibitory effects of transforming growth factor-ß and 1,25-dihydroxy-vitamin D3 on cultured epithelial cells – relationships to plasminogen activation, University of Helsinki, 1995. 

Jussi Taipale, Ph.D.: Latent transforming growth factor-ß as a component of the extracellular matrix, University of Helsinki, 1996.

Jouko Lohi, M.D. Ph.D: Regulation of matrix metalloproteinase gene expression and proteolytic activation in fibroblastic cells, University of Helsinki, 1996.

Juha Saharinen, Ph.D.: Interactions of small latent transforming growth factor-betas with their binding proteins, LTBPs, University of Helsinki,  2000.

Christine Unsöld, Ph.D.: TGF-ß binding proteins in the extracellular matrix of cutaneous cells, Univ. Münster, 2000. (Supervision shared with Leena Bruckner-Tuderman.)

Kaisa Lehti, Ph.D.: Membrane-type-1 matrix metalloproteinase in pericellular proteolysis and cell migration, University of Helsinki, 2002. 

Marko Hyytiäinen, Ph.D.: Latent TGF-ß binding protein LTBP-2: Association with the extracellular matrix and effects on cell adhesion. University of Helsinki, 2004.

Sara Wickström, M.D. Ph.D.: Endostatin modulation of pericellular proteolysis. Thesis accepted with high honors (kunniamaininta), University of Helsinki, 2004.

Sara Illman, Ph.D.:  Molecular biology and functions of epilysin (MMP-28). University of Helsinki, 2007. (Supervision shared with Jouko Lohi).

Piia Vehviläinen, Ph.D.: Latent TGF-beta binding proteins: Adhesive functions, matrix association and  potential roles in cancer. University of Helsinki, 2010.

Co-supervision with docent Katri Koli:

Anna K. Kantola, Ph.D.;Latent TGF-β binding proteins -3 and -4: transcriptional control and extracellular matrix targeting. University of Helsinki, 2010

Affiliation Expiration31/01/2017
Further information on the affiliation

Curriculum Vitae

Latest publications

  1. EGF/EGFR upregulates and cooperates with Netrin-4 to protect glioblastoma cells from DNA damage-induced senescence

    Li, L., Huang, Y., Gao, Y., Shi, T., Xu, Y., Li, H., Hyytiäinen, M., Keski-Oja, J., Jiang, Q., Hu, Y. & Du, Z., 4 Dec 2018, In : BMC Cancer. 18, 10 p., 1215.

    Research output: Contribution to journalArticleScientificpeer-review

  2. Motility of glioblastoma cells is driven by netrin-1 induced gain of stemness

    Ylivinkka, I., Sihto, H., Tynninen, O., Hu, Y., Laakso, A., Kivisaari, R., Laakkonen, P., Keski-Oja, J. & Hyytiainen, M., 9 Jan 2017, In : Journal of Experimental and Clinical Cancer Research (Online). 36, 18 p., 9.

    Research output: Contribution to journalArticleScientificpeer-review

  3. Netrin-1: A regulator of cancer cell motility?

    Ylivinkka, I., Keski-Oja, J. & Hyytiainen, M., Nov 2016, In : European Journal of Cell Biology. 95, 11, p. 513-520 8 p.

    Research output: Contribution to journalReview ArticleScientificpeer-review

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Latest activities

  1. Finska Läkaresällskapets Årsmöte

    Jorma Keski-Oja (Speaker: Presenter)
    30 Jan 2015

    Activity: Participating in or organising an event typesPublic Talks

  2. Suomen Solubiologit ry:n juhlaseminaari

    Jorma Keski-Oja (Speaker: Presenter)
    6 Nov 2014

    Activity: Participating in or organising an event typesPublic Talks

  3. Painatuslupalausunto FM Liisa Uotilan väitöskirjatyöstä

    Jorma Keski-Oja (Participant)
    2014 → …

    Activity: Other activity typesTypes for other activities - External teaching and subject coordination

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Latest prizes

  1. Medal of the Finnish Society or Dermatology

    Jorma Keski-Oja (Recipient), 2015

    Prize: Prizes and awards

  2. J. W. Runebergs pris 2015

    Jorma Keski-Oja (Recipient), 30 Jan 2015

    Prize: Prizes and awards

View all (8) »

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