Juha Klefström

Person

Latest publications

  1. Pharmacological reactivation of MYC-dependent apoptosis induces susceptibility to anti-PD-1 immunotherapy

    Haikala, H. M., Anttila, J. M., Marques, E., Raatikainen, T., Ilander, M., Hakanen, H., Ala-Hongisto, H., Savelius, M., Balboa, D., Von Eyss, B., Eskelinen, V., Munne, P., Nieminen, A. I., Otonkoski, T., Schüler, J., Laajala, T. D., Aittokallio, T., Sihto, H., Mattson, J., Heikkilä, P. & 7 othersLeidenius, M., Joensuu, H., Mustjoki, S., Kovanen, P., Eilers, M., Leverson, J. D. & Klefström, J., 6 Feb 2019, In : Nature Communications. 10, 17 p., 620.

    Research output: Contribution to journalArticleScientificpeer-review

  2. Discovery of Selective Matriptase and Hepsin Serine Protease Inhibitors: Useful Chemical Tools for Cancer Cell Biology

    Damalanka, V. C., Han, Z., Karmakar, P., O'Donoghue, A. J., La Greca, F., Kim, T., Pant, S. M., Helander, J., Klefström, J., Craik, C. S. & Janetka, J. W., 24 Jan 2019, In : Journal of Medicinal Chemistry. 62, 2, p. 480-490 11 p.

    Research output: Contribution to journalArticleScientificpeer-review

  3. Design, Synthesis, and Testing of Potent, Selective Hepsin Inhibitors via Application of an Automated Closed-Loop Optimization Platform

    Pant, S. M., Mukonoweshuro, A., Desai, B., Ramjee, M. K., Selway, C. N., Tarver, G. J., Wright, A. G., Birchall, K., Chapman, T. M., Tervonen, T. A. & Klefström, J., 24 May 2018, In : Journal of Medicinal Chemistry. 61, 10, p. 4335-4347 13 p.

    Research output: Contribution to journalArticleScientificpeer-review

View all (46) »

Latest activities

  1. Doctoral thesis supervision / Eskelinen

    Juha Klefström (Supervisor)
    2011 → …

    Activity: Examination typesSupervisor or co-supervisor of doctoral thesis

  2. Doctoral thesis supervision / Marques

    Juha Klefström (Supervisor)
    2011 → …

    Activity: Examination typesSupervisor or co-supervisor of doctoral thesis

  3. Karolinska Institutet (External organisation)

    Juha Klefström (Assessment)
    2011

    Activity: Membership typesMembership or other role in review committee

View all (41) »

Latest prizes

  1. UCSF postdoctoral grant

    Juha Klefström (Recipient), 1999

    Prize: Prizes and awards

  2. EMBO long-term fellowship

    Juha Klefström (Recipient), 1996

    Prize: Prizes and awards

  3. EMBO short-term fellowship

    Juha Klefström (Recipient), 1996

    Prize: Prizes and awards

View all (3) »

Latest projects

  1. PREDECT

    Verschuren, E., Kallioniemi, O., Klefström, J., Monni, O. & Kovanen, P.

    01/02/201131/01/2016

    Project: Research project

View all (1) »

ID: 45743