Michael Wrzaczek


Description of research and teaching

The main research focus of my group is to understand the molecular foundation of how receptor-like kinases (RLKs) are integrated with reactive oxygen species (ROS)-mediated signaling. On a physiological level we investigate how RLKs and ROS function in stress adaptation and plant development. Starting from the regulation of ROS-induced cell death we aim to understand also other aspects of ROS signaling, such as plant development.
We analyze the function of receptor-like protein kinases in ROS sensing. In particular the CYSTEINE-RICH RECEPTOR-LIKE KINASES (CRKs) are interesting proteins with a novel lectin-like ectodomains structure. In higher plants this protein family has undergone drastic expansions. Aleksia Vaattovaara is collaborating with Dr. Jarkko Salojärvi to understand the complex evolution of the CRKs and related proteins families address the reasons for the differential expansion of the CRKs in different plant families. Dr. Sachie Kimura is interested in how CRKs participate in control of extracellular ROS production and the coordination of systemic signaling in plants. Kerri Hunter is aiming to understand cell biological aspects of CRK function and to identify the protein complexes harboring CRKs.
Besides research projects I am interested in Unix, Linux/BSD and Perl-scripting and introduce biologists to those computer tools. I have been teaching programming for biologists for several years at the University of Helsinki. Currently I am teaching plant biochemistry and cell biology as well as plant genome evolution.

Education information

Docent, University of Helsinki, Finland, 2011

Education information

PhD, University of Vienna, Austria, 2004

Education information

Master of Science, University of Vienna, Austria, 2001

Curriculum Vitae

Latest publications

  1. Accepted/In press

    CRK2 enhances salt tolerance by regulating callose deposition in connection with PLDα1: CRK2 cell biology in salt stress

    Hunter, K., Kimura, S., Rokka, A., Tran, C., Toyota, M., Kukkonen, J. P. & Wrzaczek, M., May 2019, (Accepted/In press) In : Plant Physiology.

    Research output: Contribution to journalArticleScientificpeer-review

  2. Arabidopsis RCD1 coordinates chloroplast and mitochondrial functions through interaction with ANAC transcription factors

    Shapiguzov, A., Vainonen, J., Hunter, K. A., Tossavainen, H. P. M., Tiwari, A., Järvi, S., Hellman, M. H., Aarabi, F., Alseekh, S., Wybouw, B., Van Der Kelen, K., Nikkanen, L., Krasensky-Wrzaczek, J., Sipari, N. H., Keinänen, M., Tyystjaervi, E., Rintamäki, E., De Rybel, B., Salojärvi, J. T., Van Breusegem, F. & 6 othersFernie, A. R., Brosche, M. J., Permi, P. E. I., Aro, E-M., Wrzaczek, M. A. & Kangasjärvi, J. S., 15 Feb 2019, In : eLife. 8, 35 p., e43284.

    Research output: Contribution to journalArticleScientificpeer-review

  3. Mechanistic insights into the evolution of DUF26-containing proteins in land plants

    Vaattovaara, A. F. M., Brandt, B., Rajaraman, S., Safronov, O., Veidenberg, A., Luklová, M., Kangasjärvi, J. S., Löytynoja, A. P., Hothorn, M., Salojärvi, J. T. & Wrzaczek, M. A., 8 Feb 2019, In : Communications Biology. 2, 56.

    Research output: Contribution to journalArticleScientificpeer-review

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Latest activities

  1. King Abdullah University of Science and Technology (KAUST) (External organisation)

    Michael Wrzaczek (Board member)
    15 May 2019

    Activity: Membership typesMembership or other role in review committee

  2. RLKs in ROS signaling and vice versa

    Michael Wrzaczek (Speaker)
    30 Apr 2019

    Activity: Talk or presentation typesInvited talk

  3. Plant Cell Walls

    Karen Sims-Huopaniemi (Member of organizing committee), Anna Kärkönen (Chair of organizing committee), Michael Alois Wrzaczek (Member of organizing committee), Sari Kristiina Hilden (Member of organizing committee)
    18 Feb 201922 Feb 2019

    Activity: Participating in or organising an event typesOrganisation and participation in conferences, workshops, courses, seminars

View all (84) »

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