Minna Poranen

Person

Description of research and teaching

Molecular biology of prokaryotic viruses, especially dsRNA viruses; virus assembly; in vitro self-assembly systems; RNA translocation and replication; exploitation and engineering of viral processes for synthetic biology applications; molecular evolution of nucleic acid and nucleotide processing enzymes of Bacteria, Archaea, Eukarya, and their viruses; viral RNA-dependent RNA polymerases.

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Further information on the affiliationPrincipal Investigator in the Faculty of Biological and Environmental Sciences (2009-); Academy Research Fellow (2011-2016); Title of Docent in Molecular virology (2009-); Acting University Lecturer in Molecular Virology (2007-2011; part-time position); Principal Investigator in the Academy of Finland Research programme on Synthetic Biology (FinSynBio; 2013-2017); University Lecturer, Department of Biosciences (September 2016-)

Highlighted publications

  1. Accepted/In press

    Multiple liquid crystalline geometries of highly compacted nucleic acid in a dsRNA virus

    Ilca, S., Sun, X., El Omari, K., Kotecha, A., Haas, F. D., DiMaio, F., Grimes, J. M., Stuart, D. I., Poranen, M. M. & Huiskonen, J. T., 8 Mar 2019, (Accepted/In press) In : Nature.

    Research output: Contribution to journalArticleScientificpeer-review

  2. Synthetic biology approach for plant protection using dsRNA

    Niehl, A., Soininen, M., Poranen, M. M. & Heinlein, M., Sep 2018, In : Plant biotechnology journal. 16, 9, p. 1679–1687 9 p.

    Research output: Contribution to journalArticleScientificpeer-review

  3. Dual Role of a Viral Polymerase in Viral Genome Replication and Particle Self-Assembly

    Sun, X., Ilca, S. L., Huiskonen, J. T. & Poranen, M. M., 2018, In : mBio. 9, 5, 14 p., ARTN e01242-18.

    Research output: Contribution to journalArticleScientificpeer-review

  4. Double-stranded RNA virus outer shell assembly by bona fide domain-swapping

    Sun, Z., El Omari, K., Sun, X., Ilca, S., Kotecha, A., Stuart, D., Poranen, M. M. & Huiskonen, J. T., Mar 2017, In : Nature Communications. 8, p. 14814

    Research output: Contribution to journalArticleScientificpeer-review

  5. Initiation of RNA Polymerization and Polymerase Encapsidation by a Small dsRNA Virus

    Collier, A. M., Lyytinen, O. L., Guo, Y. R., Toh, Y., Poranen, M. M. & Tao, Y. J., Apr 2016, In : PLoS Pathogens. 12, 4, 26 p., 1005523.

    Research output: Contribution to journalArticleScientificpeer-review

  6. Common structural core of three-dozen residues reveals intersuperfamily relationships

    Mönttinen, H. A. M., Ravantti, J. J. & Poranen, M. M., 2016, In : Molecular Biology and Evolution. 33, 7, p. 1697-1710 14 p.

    Research output: Contribution to journalArticleScientificpeer-review

  7. Automated structural comparisons clarify the phylogeny of the right-hand-shaped polymerases

    Mönttinen, H. A. M., Ravantti, J. J., Stuart, D. I. & Poranen, M. M., 2014, In : Molecular Biology and Evolution. 31, 10, p. 2741-2752 12 p.

    Research output: Contribution to journalArticleScientificpeer-review

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Latest activities

  1. Co-supervisor of PhD thesis / Veera Brusila

    Jarkko Hantula (Co-supervisor), Hannu Fritze (Co-supervisor), Minna Poranen (Co-supervisor)
    2019 → …

    Activity: Examination typesSupervisor or co-supervisor of doctoral thesis

  2. 13th International dsRNA Symposium 2018

    Minna Poranen (Invited speaker)
    24 Sep 201828 Sep 2018

    Activity: Talk or presentation typesInvited talk

  3. Viruses of Microbes 2018: EMBO conference on Viruses of Microbes V

    Minna Poranen (Invited speaker)
    9 Jul 201813 Jul 2018

    Activity: Talk or presentation typesInvited talk

View all (95) »

Latest prizes

  1. Excellence in Master Thesis Supervision Award, 2005

    Minna Poranen (Recipient), 23 Feb 2006

    Prize: Prizes and awards

  2. Viikki Biocenter Dissertation Prize, 2000

    Minna Poranen (Recipient), 20 Nov 2000

    Prize: Prizes and awards

View all (3) »

Latest projects

  1. Novel RNA-mediated therapies for virus infections

    Hukkanen, V. & Poranen, M.

    Jane and Aatos Erkko Foundation

    01/01/201831/12/2020

    Project: Research project

  2. Viral RNA Replication Complexes and Transcripts as Targets for Antiviral Drug Discovery

    Poranen, M.

    Sigrid Juselius Foundation

    01/04/2016 → …

    Project: Research project_Research

View all (7) »

ID: 25829