Rainer Lehtonen

Person

Further information on the affiliation01.04.2013- Systems Biology Research Group and Tumor Genomics Research Group Center of Excellence in Cancer Genetics Institute of Biomedicine & Genome-Scale Biology Research Program Faculty of Medicine Biomedicum Helsinki University of Helsinki 01.02.2009 - 31.03.2013 Metapopulation Research Group (group leader: Professor Ilkka Hanski) Department of Biological and Environmental Sciences 15.05.2000-31.01.2009 Tumor Genomics Group (group leader: Lauri A Aaltonen, Professor of Tumor Genomics, University of Helsinki and Research Professor of the Academy of Finland), Genome Scale Biology Research Program, Department of Medical Genetics/ Biomedicum.

Curriculum Vitae

RAINER LEHTONEN

PhD, Docent in Genetics

Curriculum vitae

Laboratory  

Systems Biology of Drug Resistance in Cancer (Hautaniemi Lab)

Institute of Biomedicine & Genome-Scale Biology Research Program

Faculty of Medicine

Biomedicum Helsinki

University of Helsinki

Postal address: PL 63, 00014 University of Helsinki

Street address: Haartmaninkatu 8, 00290 Helsinki  

Mobile +358 504018035 (preferred)

Lab +358 504486327 Lab2 0294125407

rainer.lehtonen@helsinki.fi  

Lab: http://research.med.helsinki.fi/gsb/hautaniemi/O

Tuhat: http://tuhat.halvi.helsinki.fi/portal/en/person/rjlehton

HERCULES: http://www.project-hercules.eu/

 

Home 

Suomenlinna C7

00190 Helsinki

 

PERSONAL INFORMATION

Date and place of birth

21 April 1959, Längelmäki, Finland

Nationality Finnish

 

DEGREES IS SCIENCE

8/2006

PhD degree in Medical Genetics, Faculty of Medicine, Department of Medical Genetics, University of Helsinki, Finland. PhD-thesis: "The Role of FH (fumarase) in tumorigenesis”, Yliopistopaino 2006

9/2005

MSc degree in Genetics, Faculty of Biosciences, Department of Biological and Environmental Sciences, University of Helsinki, Finland. MSc-thesis: “ Fumarase Mutations In Nonsyndromic Uterine Leiomyomas”, University of Helsinki 2005. In addition to genetics the MSc degree includes studies in animal physiology and morphology and ecology.

 

OTHER EDUCATION                                             

12/2008

University Pedagogy I, University of Helsinki. Finland.  5 Cr

6/1999

Radiation Safety Work Management Diploma, Laboratory of Radiochemistry, University of Helsinki, Finland

12/1997

Team Leadership Training in Hotel and Restaurant Business, Arctia Oy (PLC), Helsinki, Finland.

12/1996

Quality Management In Hotel and Restaurant Business, Arctia Oy (PLC), Arctia Hotel Partners Oy (PLC), organized by Haaga Institute (currently Haaga-Helia University of Applied Sciences), Helsinki, Finland. 1650 hours studies including financial leadership, sale & marketing and personal management completed during 1.1.1996-31.12.1996.

1/1991

Hotel and Restaurant Manager Training, Kantaravintolat Oy (PLC), Helsinki, Finland. Studies including financial leadership, sale & marketing and personal management completed during 5.2.1990-30.1.1991.

8/1989

Education for Middle Management Personnel in Hotel and Restaurant Business, Haaga Institute (currently Haaga-Helia University of Applied Sciences), Helsinki, Finland. 420 hours studies including financial leadership, sale & marketing, personal management and science of law completed during 8.2.1988-10.3.1989.

 

CURRENT POSITION

4/2013-      

Senior Researcher, Systems Biology of Drug Resistance in Cancer

 

PREVIOUS RESEARCH POSITIONS

3/2009-3/2013                                      

Senior Researcher, Metapopulation Research Group (group leader: Professor Ilkka Hanski, Department of Biological and Environmental Sciences, University of Helsinki). Leader of the Glanville fritillary butterfly genome and genetics project in the Metapopulation Research Group. During the project the whole genome of the Glanville fritillary butterfly will be sequenced using next-generation sequencing technologies followed by large scale population based SNP detection. Impact of genetic variation will be analyzed on individual, population, metapopulation, and evolutionary levels. The project is funded by European Research Council (ERC) and the Academy of Finland for five years.  

 6/2006-1/2009                                     

Post-Doctoral fellow, Tumor Genomics Group (group leader: Lauri A Aaltonen, Professor of Tumor Genomics, University of Helsinki and Research Professor of the Academy of Finland), Genome Scale Biology Research Program, University of Helsinki, Department of Medical Genetics/ Biomedicum/ University of Helsinki.    

9/2007-8/2008

Doctoral Research fellow, Foundation of the Finnish Cancer Institute. Project: “Implementation of phenotype-genotype databases and bioinformatics      tools for registry-based identification of novel cancer susceptibility genes”.

5/2000-5/2006

PhD student, Tumor Genomics Group (group leader: Lauri A Aaltonen,  Research Professor of the Academy of Finland), Center of Excellence in Disease Genetics/ Academy of Finland, Molecular and Cancer Biology Research Program, Department of Medical Genetics/ Biomedicum/ University of Helsinki.

 

OTHER POSITIONS

8/1998-8/1999

Product Manager (entertainment services), Soivios Oy (PLC), Espoo, Finland

 5/1995-8/1998

Project Manager (restaurant and hotel business development), Arctia Oy, Scandic Hotels Oy (PLC), Helsinki, Finland

1/1989-4/1995

Restaurant Manager, Arctia Oy (PLC), Helsinki, Finland

5/1985-1/1989

Restaurant Manager, Hämäläisten Ravintola Oy (PLC)

9/1981-4/1985

Waiter/ cashier/ bartender, Hämäläisten Ravintola Oy (PLC)

 

SUPERVISIONS

MSc and Doctoral thesis

2010-2016

MSc thesis: Wong Swee Chong, “Computational pipe-line for design and analysis of Sequenom genotyping assays”. Co-supervised with Sirkka-Liisa Varvio.

Doctoral thesis: Quantitative and population genetics of the Glanville fritillary butterfly (Melitaea cinxia)

9/2010

Eevi Kaasinen, “Gene Identification of Recessively Inherited Right Isomerism”, grade: laudatur, co-supervised with Dr. Kristiina Aittomäki

5/2008

Sirkku Karinen, “Computational Identification of Compound Heterozygotes using Haplotypes”, co-supervised with DTech Sampsa Hautaniemi and Dr. Hannu Toivanen 

 

SELECTED ACADEMIC ACTIVITIES

2005-2009

Representative of the Tumor Genomics Group in the Nordic Network of Excellence in Disease Genetics Consortium

1/2006-12/2007

Member of the Privacy Protection Board of the University of Helsinki

Latest publications

  1. Alternative splicing discriminates molecular subtypes and has prognostic impact in diffuse large B-cell lymphoma

    Leivonen, S-K., Taskinen, M., Cervera, A., Karjalainen-Lindsberg, M-L., Delabie, J., Holte, H., Lehtonen, R., Hautaniemi, S. & Leppa, S. 25 Aug 2017 In : Blood cancer journal. 7, 10 p., 596

    Publication: Contribution to journalA1 Refereed journal article

  2. Genetic effects on life-history traits in the Glanville fritillary butterfly

    Duplouy, A., Wong, S. C., Corander, J., Lehtonen, R. & Hanski, I. 25 May 2017 In : PeerJ. 5, 23 p., 3371

    Publication: Contribution to journalA1 Refereed journal article

  3. Deltex-1 mutations predict poor survival in diffuse large B-cell lymphoma

    Meriranta, L., Pasanen, A., Louhimo, R., Cervera, A., Alkodsi, A., Autio, M., Taskinen, M., Rantanen, V., Karjalainen-Lindsberg, M-L., Holte, H., Delabie, J., Lehtonen, R., Hautaniemi, S. & Leppä, S. May 2017 In : Haematologica. 102, 5, p. E195-E198 4 p.

    Publication: Contribution to journalB1 Unrefereed journal article

View all (59) »

Latest activities

  1. Computational analysis methods for studying regulation of transcription

    Lehtonen, R. (Member of thesis committee / follow-up group)
    2015 → …

    Activity: ExaminationMember of doctoral thesis committee / follow-up group

  2. Transcriptomics and metabolomics analyses in obesity-discordant monozygotic twins

    Lehtonen, R. (Member of thesis committee / follow-up group)
    2015 → …

    Activity: ExaminationMember of doctoral thesis committee / follow-up group

  3. Genetics of statin use and related adverse events

    Lehtonen, R. (Member of thesis committee / follow-up group)
    Oct 2015 → …

    Activity: ExaminationMember of doctoral thesis committee / follow-up group

View all (20) »

Education

Ylioppilastutkinto

ID: 75403