Tapani Viitala

Person

    Research areas

  • 317 Pharmacy - Pharmaceutical nanotechnology, Cell model membranes, Targeted drug and gene delivery, Physico-Chemical proerties of drugs, In vitro drug discovery and development methods
  • 221 Nano-technology - Organic thin films, Ultrathin organic films, Self-assembled monolayers, Lipid bilayers, Liposomes, Nanoparticles, Langmuir- and Langmuir-Blodgett technologies
  • 116 Chemical sciences - Physical Chemistry, Surface and Colloid Chemistry, Physico-Chemical characterisation, Surface specific analysis methods, Quartz crystal microbalance, Surface plasmon resonance spectroscopy, Spectroscopy, Contact angle, Surface tension, Surface energy, Surface active agents

Description of research and teaching

My research focuses on utilizing nanotechnology and physico-chemical analysis techniques (e.g. SPR and QCM) for developing complementary and alternative in vitro methodologies for existing biological assays for preclinical drug research and discovery purposes. I was awarded a 5 year Academy Research Fellow position in August 2010 for research on molecularly controlled cell surface models as a platform for targeted drug and gene delivery and release optimization.
Apart from collaborating closely with CDR I also collaborate with departments from several national and international universities (e.g. Åbo Akademi, Aalto University, Tampere University of Technology, and University of Montreal) and companies (e.g. Bionavis Ltd, Biolin Scientific Oy and Accurion GmbH).
I am lecturing in the advanced Physical Pharmacy course. I integrate my research into teaching by supervising master´s and PhD students within my research focus areas.

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Highlighted publications

  1. Real-Time Label-Free Monitoring of Nanoparticle Cell Uptake

    Suutari, T., Silen, T., Sen Karaman, D., Saari, H., Desai, D., Kerkelä, E., Laitinen, S., Hanzlikova, M., Rosenholm, J. M., Yliperttula, M. & Viitala, T. 7 Dec 2016 In : Small. 12, 45, p. 6289-6300 12 p.

    Research output: Scientific - peer-reviewArticle

  2. Feasibility Study of the Permeability and Uptake of Mesoporous Silica Nanoparticles across the Blood-Brain Barrier

    Baghirov, H., Karaman, D., Viitala, T., Duchanoy, A., Lou, Y-R., Mamaeva, V., Pryazhnikov, E., Khiroug, L., Davies, C. D. L., Sahlgren, C. & Rosenholm, J. M. 22 Aug 2016 In : PLoS One. 11, 8, 22 p., 0160705

    Research output: Scientific - peer-reviewArticle

  3. Rational design of liposomal drug delivery systems, a review: Combined experimental and computational studies of lipid membranes, liposomes and their PEGylation

    Bunker, A., Magarkar, A. & Viitala, T. Oct 2016 In : Biochimica et Biophysica Acta. Biomembranes. 1858, 10, p. 2334-2352 19 p.

    Research output: Scientific - peer-reviewArticle

  4. Printing technologies in fabrication of drug delivery systems

    Kolakovic, R., Viitala, T., Ihalainen, P., Genina, N., Peltonen, J. & Sandler, N. Dec 2013 In : Expert Opinion on Drug Delivery. 10, 12, p. 1711-1723 13 p.

    Research output: Scientific - peer-reviewReview Article

  5. Fluid dynamics modeling for synchronizing surface plasmon resonance and quartz crystal microbalance as tools for biomolecular and targeted drug delivery studies

    Viitala, T., Liang, H., Gupta, M., Zwinger, T., Yliperttula, M. & Bunker, A. 15 Jul 2012 In : Journal of Colloid and Interface Science. 378, 1, p. 251-259 9 p.

    Research output: Scientific - peer-reviewArticle

  6. An impedance QCM study on the partitioning of bioactive compounds in supported phospholipid bilayers

    Kannisto, K., Murtomäki, L. & Viitala, T. 15 Apr 2011 In : Colloids and Surfaces B: Biointerfaces. 86, 2, p. 298-304 7 p.

    Research output: Scientific - peer-reviewArticle

  7. Silymarin loaded liposomes for hepatic targeting: In vitro evaluation and HepG2 drug uptake

    Elmowafy, M., Viitala, T., Ibrahim, H. M., Abu-Elyazid, S. K., Samy, A., Kassem, A. & Yliperttula, M. 9 Oct 2013 In : European Journal of Pharmaceutical Sciences. 50, 2, p. 161-171 11 p.

    Research output: Scientific - peer-reviewArticle

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Latest activities

  1. European Journal of Pharmaceutics and Biopharmaceutics (Journal)

    Viitala, T. (Reviewer)
    28 Aug 2017

    Activity: Publication peer-review and editorial workPeer review of manuscripts

  2. Pre-examiner of PhD thesis (Konstantin Tamarov)

    Viitala, T. (Pre-examiner)
    25 Aug 2017

    Activity: ExaminationPre-examiner of doctoral thesis

  3. 30 years of drug delivery research, Kuopio, Finland

    Viitala, T. (Attendee), Viitala, T. (Poster Presentation)
    11 Jun 201713 Jun 2017

    Activity: Participating in or organising an eventOrganisation and participation in conferences, workshops, courses, seminars

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Education

Fil. toht., kemia

ID: 80994