Downregulation of tyrosine hydroxylase phenotype after AAV injection above substantia nigra: Caution in experimental models of Parkinson's disease

Research output: Contribution to journalArticleScientificpeer-review

Katrina Albert, Merja H. Voutilainen, Andrii Domanskyi, T. Petteri Piepponen, Sari Ahola, Raimo K. Tuominen, Christopher Richie, Brandon K. Harvey, Mikko Airavaara

LanguageEnglish
JournalJournal of Neuroscience Research
Volume97
Issue number3
Pages346-361
Number of pages16
ISSN0360-4012
DOIs
Publication statusPublished - Mar 2019
MoE publication typeA1 Journal article-refereed

    Research areas

  • adeno-associated virus, alpha-synuclein, DIO, dopamine, GFP, Parkinson's disease, substantia nigra, HUMAN ALPHA-SYNUCLEIN, MIDBRAIN DOPAMINE NEURONS, RAT MODEL, MEDIATED OVEREXPRESSION, MESSENGER-RNA, GENE-TRANSFER, MOUSE MODEL, PROTEIN, CALCIUM, NEURODEGENERATION

External organisations

Albert, Katrina
  • Univ Helsinki, University of Helsinki, Inst Biotechnol, Dev Biol Program
Voutilainen, Merja H.
  • Univ Helsinki, University of Helsinki, Inst Biotechnol, Dev Biol Program
Domanskyi, Andrii
  • Univ Helsinki, University of Helsinki, Inst Biotechnol, Dev Biol Program
Piepponen, T. Petteri
  • Univ Helsinki, University of Helsinki, Fac Pharm, Div Pharmacol & Pharmacotherapy, Clin Pharm Grp
Ahola, Sari
  • Univ Helsinki, University of Helsinki, Inst Biotechnol, Dev Biol Program
Tuominen, Raimo K.
  • Univ Helsinki, University of Helsinki, Fac Pharm, Div Pharmacol & Pharmacotherapy, Clin Pharm Grp
Richie, Christopher
  • NIDA, NIH National Institute on Aging (NIA), NIH National Institute on Drug Abuse (NIDA), National Institutes of Health (NIH) - USA, Chem & Drug Metab, Intramural Res Program, NIH
Harvey, Brandon K.
  • NIDA, NIH National Institute on Aging (NIA), NIH National Institute on Drug Abuse (NIDA), National Institutes of Health (NIH) - USA, Chem & Drug Metab, Intramural Res Program, NIH
Airavaara, Mikko
  • Univ Helsinki, University of Helsinki, Inst Biotechnol, Dev Biol Program

ID: 122703924