Nano LC-MS using capillary columns enables accurate quantification of modified ribonucleosides at low femtomol levels.

Research output: Contribution to journalArticleScientificpeer-review

Leif Peter Sarin, Sandra D. Kienast, Johannes Leufken, Robert L. Ross, Agnieszka Dziergowska, Katarzyna Debiec, Elzbieta Sochacka, Patrick A. Limbach, Christian Fufezan, Hannes C. Drexler, Sebastian A. Leidel

LanguageEnglish
JournalRNA
Volume24
Issue number10
Pages1403-1417
Number of pages15
ISSN1355-8382
DOIs
Publication statusPublished - Oct 2018
Externally publishedYes
MoE publication typeA1 Journal article-refereed

    Research areas

  • 1182 Biochemistry, cell and molecular biology - transfer RNA, Liquid chromatography tandem mass spectrometry (LC-MS/MS), Nucleoside analysis
  • 116 Chemical sciences - Porous graphitic carbon
  • transfer RNA modification, mass spectrometry, porous graphitic carbon, stable isotope labeling, nanoflow liquid chromatography, POROUS GRAPHITIC CARBON, TRANSFER-RNA MODIFICATIONS, PERFORMANCE LIQUID-CHROMATOGRAPHY, TANDEM MASS-SPECTROMETRY, STATIONARY-PHASE, TRANSLATION, NUCLEOSIDES, YEAST, SEPARATION, DISEASES

External organisations

Sarin, Leif Peter
  • Max Planck Institute for Molecular Biomedicine
  • University of Muenster
Kienast, Sandra D.
  • Max Planck Institute for Molecular Biomedicine
  • University of Muenster
Leufken, Johannes
  • Max Planck Institute for Molecular Biomedicine
  • University of Muenster
Ross, Robert L.
  • Department of Chemistry, University of Cincinnati
Dziergowska, Agnieszka
  • Institute of Organic Chemistry, Faculty of Chemistry, Lodz University of Technology
Debiec, Katarzyna
  • Institute of Organic Chemistry, Faculty of Chemistry, Lodz University of Technology
Sochacka, Elzbieta
  • Institute of Organic Chemistry, Faculty of Chemistry, Lodz University of Technology
Limbach, Patrick A.
  • Department of Chemistry, University of Cincinnati
Fufezan, Christian
  • Institute of Plant Biology and Biotechnology, University of Münster
Drexler, Hannes C.
  • Max Planck Institute for Molecular Biomedicine
Leidel, Sebastian A.
  • Max Planck Institute for Molecular Biomedicine

ID: 94004676